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rifabutin will lower the extent or effect of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.Particularly, Be sure that you explore if you are applying any of the next in advance of using modafinil.Andre ting du bør snakke med lege eller apotek om Noen personer har rapportert at de har hatt selvmordstanker